H4K12la

1 paper1 finding

Animals1

Effects

1

Cellular senescence

upin cells1

1 study

H4K12la induces cellular senescence in cells.
“H4K12la modulates the CD38-nicotinamide adenine dinucleotide (NAD+) signaling pathway, thereby promoting AEC2 senescence”
Cells
Histone H4 Lysine 12 Lactylation Promotes the Senescence of Alveolar Epithelial Type II Cells in Chronic Obstructive Pulmonary Disease by Modulating the CD38-NAD⁺ Signaling Pathway
Aging and disease16 Oct 2025

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Histone H4 Lysine 12 Lactylation Promotes the Senescence of Alveolar Epithelial Type II Cells in Chronic Obstructive Pulmonary Disease by Modulating the CD38-NAD⁺ Signaling Pathway

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