GZMK+ CD8+ T cell and C1Q+ macrophage abundance

Age is associated with GZMK+ CD8+ T cell and C1Q+ macrophage abundance in mice.

“age-related bulk molecular changes could be attributed in part to compositional remodeling of cell-types-expansion of GZMK+ CD8+ T cells and C1Q+ macrophages”

Animalsspleenmale and females

Multimodal analysis of molecular remodeling in aging spleen identified global and cell type specific changes

bioRxiv : the preprint server for biology·21 Apr 2026Preprint