Global amyloid-beta burden

1. Medial temporal lobe volume has no effect on global amyloid-beta burden in humans.

   “MTL volumes were not consistently associated with global Aβ burden.”

   Humanscognitively unimpaired participants with a first-degree family history of Alzheimer's diseasemedial temporal lobe

   Basal Forebrain Volume is Associated With Cortical Amyloid Burden in Cognitively Unimpaired Older Adults at Varying Genetic Risk for Alzheimer's Disease

   The American journal of geriatric psychiatry. Open science, education, and practice·May 12, 2026

More on Medial temporal lobe volume

1. Nucleus basalis of Meynert volume is associated with global amyloid-beta burden in humans (Pearson r = -0.40; p = 0.004).

   “nbM, but not other BFCS regions, was found to be inversely associated with global Aβ burden (Pearson r(43) = -0.40, p = 0.004).”

   Humanscognitively unimpaired participants with a first-degree family history of Alzheimer's diseasenucleus basalis of Meynert

   Basal Forebrain Volume is Associated With Cortical Amyloid Burden in Cognitively Unimpaired Older Adults at Varying Genetic Risk for Alzheimer's Disease

   The American journal of geriatric psychiatry. Open science, education, and practice·May 12, 2026

More on Nucleus basalis of Meynert volume