Genetically predicted leucocyte telomere length
1 paper2 findings
- Humans1
Associations
2Adenocarcinoma
upin humans1
1 study
Adenocarcinoma
upin humans1
Genetically predicted leucocyte telomere length raises the risk of adenocarcinoma in humans (HRper 1 SD gTL=2.45, 95%CI: 1.69 to 3.57, p=6.5×10−6).
“particularly adenocarcinoma (HRper 1 SD gTL=2.45, 95%CI: 1.69 to 3.57, p=6.5×10−6)”
Humansoverall and particularly in never smokers
Thorax17 Jan 2024
Lung cancer
upin humans1
1 study
Lung cancer
upin humans1
Genetically predicted leucocyte telomere length raises the risk of lung cancer in humans (HRper 1 SD gTL=1.87, 95% CI: 1.49 to 2.36, p=4.0×10−7).
“Mendelian Randomization analyses supported causal associations between longer telomere length and lung cancer (HRper 1 SD gTL=1.87, 95% CI: 1.49 to 2.36, p=4.0×10−7)”
Humansoverall and particularly in never smokers
Thorax17 Jan 2024
Latest
Thorax
Phenotypic and genetically predicted leucocyte telomere length and lung cancer risk in the prospective UK Biobank
Cohort study of 371,890 peopleLung cancer