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Function-related indicator

There are 4 papers on function-related indicator in aging research: 4 observational studies in people. The newest story, Oct 17, 2026: “Combined measures better predict cardiovascular disease and diabetes”.

Biomarker

4 papers study it6 more mention it3 findings

1 new paper in 30 daysSee all 10 papers on function-related indicator

“10-year age-adjusted invasive breast cancer risk slightly decreased with FRI score [FRI = 0: 4.0%, 95% confidence interval (CI) = 3.8-4.1; FRI = 1: 3.9%, 95% CI = 3.7-4.2; FRI ≥ 2: 3.5%, 95% CI = 3.1-3.9)”
Function-related Indicators and Outcomes of Screening Mammography in Older Women: Evidence from the Breast Cancer Surveillance Consortium CohortCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021doi:10.1158/1055-9965.epi-21-0152
  • Humans4

Effects

1

Breast cancer death

no changein humans1

1 study

  1. Function-related indicator was not clearly linked with breast cancer death in humans (screening mammography cohort).

    “Risk of breast cancer death was low with minimal differences across FRI scores.”

    Humansscreening mammography cohortfemalesn = 238,849

    Function-related Indicators and Outcomes of Screening Mammography in Older Women: Evidence from the Breast Cancer Surveillance Consortium Cohort

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Associations

2

Mortality

upin humans1

1 study

  1. Function-related indicator is linked with a higher risk of mortality in humans (screening mammography cohort) (FRI = 0: 18.8%, 95% CI = 18.5-19.1; FRI = 1: 24.4%, 95% CI = 23.9-25.0; FRI ≥ 2: 39.8%, 95% CI = 38.8-40.9).

    “Risk of non-breast cancer death increased with FRI score (FRI = 0: 18.8%, 95% CI = 18.5-19.1; FRI = 1: 24.4%, 95% CI = 23.9-25.0; FRI ≥ 2: 39.8%, 95% CI = 38.8-40.9]”

    Humansscreening mammography cohort10-yearfemalesn = 238,849

    Function-related Indicators and Outcomes of Screening Mammography in Older Women: Evidence from the Breast Cancer Surveillance Consortium Cohort

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Breast cancer

downin humans1

1 study

  1. Function-related indicator is linked with a lower risk of breast cancer in humans (screening mammography cohort) (FRI = 0: 4.0%, 95% CI = 3.8-4.1; FRI = 1: 3.9%, 95% CI = 3.7-4.2; FRI ≥ 2: 3.5%, 95% CI = 3.1-3.9).

    “10-year age-adjusted invasive breast cancer risk slightly decreased with FRI score [FRI = 0: 4.0%, 95% confidence interval (CI) = 3.8-4.1; FRI = 1: 3.9%, 95% CI = 3.7-4.2; FRI ≥ 2: 3.5%, 95% CI = 3.1-3.9)”

    Humansscreening mammography cohort10-yearfemalesn = 238,849

    Function-related Indicators and Outcomes of Screening Mammography in Older Women: Evidence from the Breast Cancer Surveillance Consortium Cohort

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

More on Breast cancer

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 1May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 2Nov 2026: 05 papers in 12 months
Science Bulletin

Combined measures better predict cardiovascular disease and diabetes

An observational study compared 15 measures in 4,258,033 Chinese adults, finding better prediction of cardiovascular and diabetes outcomes with combined measures.An observational study compared 15 measures in 4,258,033 Chinese adults, finding better prediction of cardiovascular and diabetes outcomes with combined measures.

Cohort · 4,258,033 peopleDiabetes mellitus
Paper

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