FRAX HF

There are 5 papers on FRAX HF in aging research: 4 observational studies in people, 1 review.

Biomarker

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See all 9 papers on FRAX HF

“The optimal cut-off values of FRAX HF for predicting hip fractures were 1.1% for males and 3.3% for females.”
The optimal cut-off values of FRAX without BMD for predicting osteoporosis fracture risk in the older adults at Nan, ThailandOsteoporosis and sarcopenia2024doi:10.1016/j.afos.2023.12.004
  • Humans4

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1

HALP score

downin humans1

1 study
  1. HALP score is linked with lower FRAX HF in humans (type 2 diabetes mellitus) (β = -0.019, 95% CI -0.034 to -0.005, p = 0.007).

    “Multivariate linear regression further quantified that each one‐tertile decrease in HALP (tertile interval = 16.1) was associated with an approximate 0.31% increase in FRAX‐HF probability”

    Humanstype 2 diabetes mellitusfemalesn = 423

    HALP score-adjusted FRAXplus tool effectively predicts hip fracture risk in elderly women with type 2 diabetes mellitus

    BMC endocrine disorders

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Associations

2

Hip fracture

upin humans2+1.1%

2 studies
  1. FRAX HF predicts hip fracture in males (1.1%).

    “The optimal cut-off values of FRAX HF for predicting hip fractures were 1.1% for males and 3.3% for females.”

    Humansin malesmalesn = 36,042

    The optimal cut-off values of FRAX without BMD for predicting osteoporosis fracture risk in the older adults at Nan, Thailand

    Osteoporosis and sarcopenia

  2. FRAX HF predicts hip fracture in humans with BMD (AUC 0.77 (95% CI 0.71-0.83)).

    “The AUC values for predicting fracture risk using FRAX-HF with BMD (0.77 [0.71-0.83]) was highest compared to FRAX-HF without BMD (0.72 [0.65-0.80]), and adjusted FRAX-HF (0.75 [0.63-0.86]).”

    Reviewwith BMD

    Discriminatory Accuracy of Fracture Risk Assessment Tool in Asian Populations: A Systematic Review and Meta-Analysis

    Journal of bone metabolism

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Osteoporosis

upin humans1

1 study
  1. FRAX HF predicts osteoporosis in humans (AUC = 0.75).

    “the discriminative ability was acceptable for both FRAX hip fracture (HF) (AUC = 0.75) and major osteoporotic fracture (MOF) (AUC = 0.72).”

    Humansn = 2,991

    A new cut-off value of FRAX tools as an osteoporosis screening tool for Thai geriatric population

    Scientific reports

More on Osteoporosis

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