Framingham general cardiovascular disease risk equation

1. Framingham general cardiovascular disease risk equation increases high-risk classification in humans (Framingham 20.2%, WHO/ISH 2.4%, ASCVD-PCE 4.8% of participants).

   “High risk ([≥]20%) was identified in 2.4%, 4.8%, and 20.2% of participants by WHO/ISH, ASCVD-PCE, and Framingham, respectively.”

   HumansEstimated 10-year cardiovascular disease risk ≥20%; university employees in India86.3% malesn = 124

   Cardiovascular Risk Stratification Among University Employees in India: Comparison of WHO/ISH, ASCVD and Framingham Risk Models

   medRxiv·14 Oct 2026Preprint

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1. Framingham general cardiovascular disease risk equation increases estimated 10-year cardiovascular disease risk in humans (Mean estimated risk: Framingham 12.86%, WHO/ISH 5.94%, ASCVD-PCE 5.95%).

   “Mean estimated risk was 5.94% for WHO/ISH, 5.95% for ASCVD-PCE, and 12.86% for Framingham.”

   HumansUniversity employees in India without documented previous ischemic heart disease86.3% malesn = 124

   Cardiovascular Risk Stratification Among University Employees in India: Comparison of WHO/ISH, ASCVD and Framingham Risk Models

   medRxiv·14 Oct 2026Preprint

More on Estimated 10-year cardiovascular disease risk