Estimated HbA1c

1. GLP-1 receptor agonists have no effect on estimated HbA1c in humans (mean difference 0.10%, p = 0.43).

   “mean difference in A1c reduction at 24 months from 12 months of 0.10%, p-value = 0.43”

   Humansadherent to GLP-1s for 12 months then discontinued for 12 months12 months post-discontinuation

   Durability of Glycemic Improvement With and After GLP-1 Therapy in a Real-World Remote Monitoring Diabetes Program (RMDP)

   ADA Scientific Sessions 2026 abstract·5 Jun 2026

2. GLP-1 receptor agonists decrease estimated HbA1c in humans (-2.6% (SD 2.4%)).

   “Adjusted mean eA1c reduction at 24 months was greatest in the GLP-1 adherent group (−2.6%; SD 2.4%)”

   Humansuncontrolled diabetes in RMDP24 months45.4% females

   Durability of Glycemic Improvement With and After GLP-1 Therapy in a Real-World Remote Monitoring Diabetes Program (RMDP)

   ADA Scientific Sessions 2026 abstract·5 Jun 2026

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