eGFR difference

There are 4 papers on eGFR difference in aging research: 4 observational studies in people. The newest story, Oct 11, 2026: “Multiple conditions linked to differing kidney function estimates”.

Biomarker

4 papers study it11 more mention it5 findings

3 new papers in 30 daysSee all 15 papers on eGFR difference

“Individuals with eGFRdiff < -15 were associated with increased risks of death (HR, 1.37 [1.30-1.44]), MI (HR, 1.23 [1.15-1.33]), and ischemic stroke (HR, 1.19 [1.08-1.31]).”
Outcomes and Risk Factors of Widened Difference in Estimated Glomerular Filtration Rate Based on Creatinine or Cystatin C: Adjust Model Development With More Than 300,000 UK Biobank ParticipantsKidney medicine2026doi:10.1016/j.xkme.2026.101288
  • Humans4

Associations

5

Mortality

upin humans1OR 1.96

1 study
  1. eGFR difference is linked with a higher risk of mortality in humans (fully adjusted model) (OR = 1.96, 95% CI: 1.27 to 3.00, P = 0.002).

    “mortality: OR = 1.96, 95% CI: 1.27 to 3.00, P = 0.002).”

    Humansfully adjusted modeln = 26,065

    Differences between cystatin C- and creatinine-based estimated glomerular filtration rate and the risks of postoperative complications and mortality

    Journal of clinical anesthesia

Postoperative complications

upin humans1OR 1.6

1 study
  1. eGFR difference is linked with a higher risk of postoperative complications in humans (fully adjusted model) (OR = 1.60, 95% CI: 1.28 to 2.01, P < 0.001).

    “These associations remained significant after full adjustment (complications: OR = 1.60, 95% CI: 1.28 to 2.01, P < 0.001”

    Humansfully adjusted modeln = 26,065

    Differences between cystatin C- and creatinine-based estimated glomerular filtration rate and the risks of postoperative complications and mortality

    Journal of clinical anesthesia

Stroke

upin humans1HR 1.19

1 study
  1. eGFR difference is linked with a higher risk of stroke in humans (eGFRdiff < -15) (HR, 1.19 [1.08-1.31]).

    “Individuals with eGFRdiff < -15 were associated with increased risks of death (HR, 1.37 [1.30-1.44]), MI (HR, 1.23 [1.15-1.33]), and ischemic stroke (HR, 1.19 [1.08-1.31]).”

    HumanseGFRdiff < -15n = 343,854

    Outcomes and Risk Factors of Widened Difference in Estimated Glomerular Filtration Rate Based on Creatinine or Cystatin C: Adjust Model Development With More Than 300,000 UK Biobank Participants

    Kidney medicine

More on Stroke

Myocardial infarction

upin humans1HR 1.23

1 study
  1. eGFR difference is linked with a higher risk of myocardial infarction in humans (eGFRdiff < -15) (HR, 1.23 [1.15-1.33]).

    “Individuals with eGFRdiff < -15 were associated with increased risks of death (HR, 1.37 [1.30-1.44]), MI (HR, 1.23 [1.15-1.33]), and ischemic stroke (HR, 1.19 [1.08-1.31]).”

    HumanseGFRdiff < -15n = 343,854

    Outcomes and Risk Factors of Widened Difference in Estimated Glomerular Filtration Rate Based on Creatinine or Cystatin C: Adjust Model Development With More Than 300,000 UK Biobank Participants

    Kidney medicine

More on Myocardial infarction

Death

upin humans1HR 1.37

1 study
  1. eGFR difference is linked with a higher risk of death in humans (eGFRdiff < -15) (HR, 1.37 [1.30-1.44]).

    “Individuals with eGFRdiff < -15 were associated with increased risks of death (HR, 1.37 [1.30-1.44]), MI (HR, 1.23 [1.15-1.33]), and ischemic stroke (HR, 1.19 [1.08-1.31]).”

    HumanseGFRdiff < -15n = 343,854

    Outcomes and Risk Factors of Widened Difference in Estimated Glomerular Filtration Rate Based on Creatinine or Cystatin C: Adjust Model Development With More Than 300,000 UK Biobank Participants

    Kidney medicine

Latest

Dec 2025: 0Jan 2026: 1Feb 2026: 2Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 2Sep 2026: 0Oct 2026: 3Nov 2026: 010 papers in 12 months
Nephrology, Dialysis, Transplantation

Multiple conditions linked to differing kidney function estimates

Participants with four or more long-term conditions had 4.64 times the adjusted odds of a large kidney estimate mismatch compared with those reporting none.Participants with four or more long-term conditions had 4.64 times the adjusted odds of a large kidney estimate mismatch compared with those reporting none.

Cohort study of 400,000 peopleKidney

See all 15 papers on eGFR difference