Early complement and serine protease inhibitor RNA signature

1. Plasmodium berghei infection increases early complement and serine protease inhibitor RNA signature in mice.

   “we reveal a shared activation of the early complement pathway (C4b) and serine protease inhibitors (Serpin gene family) within by phenotype distinct spatial niches.”

   Animalssystemic infection; signature shared with agingPlasmodium berghei ANKA

   Spatiotemporal transcriptomic niches of complement pathway and serine protease inhibitor activation in aging and infection

   bioRxiv (Cold Spring Harbor Laboratory)·4 Nov 2024Preprint

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