2 papers2 findings
Chronological age
upin humans1
Chronological age is associated with DNA methylation variability in humans.
“increases in variability of DNA methylation with age have been observed”
Review
DNA methylation and healthy human aging
Aging cell25 Apr 2015
Cellular composition
upin humans1
Cellular composition is associated with DNA methylation variability in humans.
“cellular composition explains much of the observed variability in DNA methylation”
Humansblood
Accounting for cellular heterogeneity is critical in epigenome-wide association studies
Genome biology4 Feb 2014
Combining methylation variance with mean methylation levels improved predictions of all-cause mortality across two independent human cohorts.Combining methylation variance with mean methylation levels improved predictions of all-cause mortality across two independent human cohorts.