DLB polygenic score

1. DLB polygenic score has no effect on dementia in humans (HR 1.17, 95% CI 0.91–1.47).

   “However, DLB‐PGS was not associated with risk of dementia (HR: 1.17, 95% CI: 0.91‐1.47, p = 0.2).”

   Humansin individuals with bipolar disordern = 2,238

   Genetic risk for Alzheimer's disease is associated with dementia in patients with bipolar disorder

   AAIC 2025 abstract·23 Dec 2025

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