Default mode network segregation

Biomarker

1 paper studies it4 findings

  • Humans1

Effects

1

Speech revisions

mediatesin humans1

1 study
  1. Default mode network segregation mediates speech revisions in humans.

    “DMN segregation also partially mediated the relationship between age and revisions.”

    Humansn = 252

    Age-Related Differences in Resting-State Functional Connectivity Predict Specific Patterns of Speech Disfluency

    Neurobiology of language (Cambridge, Mass.)

Associations

3

Episodic and relational memory

upin humans1

1 study
  1. Default mode network segregation is associated with episodic and relational memory in humans.

    “Higher DMN segregation is associated with better episodic and relational memory across the PREVENT cohort”

    Humanscognitively healthyn = 210

    Genetic risk of Alzheimer's disease is associated with loss of brain network segregation in midlife

    Communications biology

APOE

downin humans1

1 study
  1. APOE is associated with default mode network segregation in humans.

    “accompanied by greater longitudinal decline in the DMN over two years, relative to non-carriers”

    Humanscognitively healthybraintwo yearsn = 210

    Genetic risk of Alzheimer's disease is associated with loss of brain network segregation in midlife

    Communications biology

More on APOE

Speech disfluencies

downin humans1

1 study
  1. Default mode network segregation predicts speech disfluencies in humans.

    “higher DMN segregation predicted lower overall disfluencies, repetitions, and revisions.”

    Humansn = 252

    Age-Related Differences in Resting-State Functional Connectivity Predict Specific Patterns of Speech Disfluency

    Neurobiology of language (Cambridge, Mass.)

Latest

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