Default mode network functional connectivity

Biomarker

2 papers2 findings

  • Humans2

Upstream

1

Female sex

upin humans1

1 study
  1. Female sex increases default mode network functional connectivity in humans.

    “Females show much higher FC mainly within the default mode network”

    Humansbrain

    Lifespan Changes in Functional Brain Networks: A Study Using fMRI from Three Human Connectome Project Studies and Alzheimers Disease Neuroimaging Initiative

    AAIC 2025 abstract23 Dec 2025

Associations

1

Reaction time

upin humans1

1 study
  1. Default mode network functional connectivity is associated with reaction time in humans.

    “FC between the left superior frontal gyrus and right middle temporal pole was associated with the late aftereffect reflected by prolonged reaction time.”

    Humansn = 36

    Default mode network functional connectivity is associated with intention interference in healthy aging

    Brain imaging and behavior29 Sep 2026

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