Salience Network functional connectivity

Salience Network functional connectivity is associated with episodic memory in humans (β = - 0.070, pFDR = 0.046, marginal r2 = 0.179).

“Salience Network connectivity moderated the hippocampal-memory relationship (β = - 0.070, pFDR = 0.046, marginal r2 = 0.179).”

Humansmoderating the hippocampal-memory relationshipbrainfollow-upmean = 4.2 yearsn = 451

Modeling and evaluating longitudinal brain maintenance and cognitive reserve using episodic memory, brain structure, and functional connectivity in older adults

GeroScience·21 Mar 2026