DCLK1 somatic mutations

1 paper1 finding

In silico1

Associations

1

Alzheimer's disease

upin humans1

1 study

Alzheimer's disease is associated with DCLK1 somatic mutations in humans.
“a higher odds ratio to detect a somatic mutation in AD samples (6:73374221 ( KCNQ5 ), p = 0.014 and 13:36667102 ( DCLK1 ), p = 0.023).”
Humanssite 13:36667102excitatory neuron
Identifying aging and Alzheimer’s disease associated somatic mutations in excitatory neurons from the human frontal cortex using whole genome sequencing and single cell RNA sequencing data
medRxivMay 26, 2022Preprint

More on Alzheimer's disease

Latest

medRxivMay 26

Identifying aging and Alzheimer’s disease associated somatic mutations in excitatory neurons from the human frontal cortex using whole genome sequencing and single cell RNA sequencing data

Preprint: computational studyMechanisms