Biomolecules & Therapeutics
Adenine Promotes Osteogenic Differentiation and Suppresses Osteoclastogenesis
Experiments in mouse cellsInterventions
Papers on CREB phosphorylation
29 papers1 new in 30 days
Thursday, October 29
Thursday, September 3
Pharmacological Research
Spectinabilin mitigates Aβ-associated proteotoxic stress and preserves synaptic protein expression in cellular and Caenorhabditis elegans models
Experiments in mouse cellsInterventions
Monday, August 10
Journal of Pineal Research
Melatonin Suppresses Osteoclastogenesis via Inhibiting Iron/ROS-CREB/PGC-1β-Mediated Mitochondrial Biogenesis
Experiments in mouse cellsMelatonin
Sunday, June 7
ADA Scientific Sessions 2026 Abstract
GLP-1R Agonists Increase Irisin Levels in Patients with T2D through PKA/CREB-Dependent Muscle Stimulation
Cross-sectional study of 190 peopleGLP-1 receptor agonists
Friday, April 10
Biochemical Pharmacology
PRDX6 attenuates osteoporotic bone loss by restraining oxidative stress-associated osteoblast senescence
Experiments in miceCellular senescence
Saturday, March 14
International Journal of Molecular Sciences
Combined and Separate Pretreatments with L-Theanine and Aerobic Exercise Modulate Cognitive Decline Following Chronic Neuroinflammation in Rats Exposed to Lipopolysaccharide
Experiments in ratsAerobic exercise
Thursday, March 12
Journal of Advanced Research
Rejuvenation of THY1⁺ nucleus pulposus-derived stem cells promotes intervertebral disc regeneration through FGF10-FGFR1-CREB pathway and mitochondrial fission
Experiments in animalsInterventions
Tuesday, January 13
bioRxiv
Exercise-Induced Epoxy-Eicosanoids Promote Cardiomyocyte Proliferation and Post-Infarction Repair via NR4A1
Preprint: experiments in miceAerobic exercise
Wednesday, November 19
Monday, October 13
International Immunopharmacology
Sigma-1 receptor activation ameliorates age-related postoperative cognitive dysfunction by attenuating endoplasmic reticulum stress and neuroinflammation
Experiments in miceInterventions
Friday, June 13
ADA Scientific Sessions 2025 Abstract
Tirzepatide Prevents Palmitate-Induced Apoptosis, Autophagy, and Senescence in Human Cardiac Progenitor Cells
Experiments in human cellsTirzepatide
Friday, December 27
The European Journal of Neuroscience
Effects of Age and Atomoxetine on Olfactory Perception and Learning and Underlying Plasticity Mechanisms in Rats
Experiments in ratsInterventions
Saturday, December 21
Acta Neuropathologica Communications
Paradoxical attenuation of early amyloid-induced cognitive impairment and synaptic plasticity in an aged APP/Tau bigenic rat model
Experiments in ratsAPP
Friday, January 19
Journal of Pineal Research
N1-Acetyl-5-methoxykynuramine, which decreases in the hippocampus with aging, improves long-term memory via CaMKII/CREB phosphorylation
Experiments in miceInterventions
Friday, July 14
Aging and Disease
Metformin Treatment Leads to Increased HIV Transcription and Gene Expression through Increased CREB Phosphorylation and Recruitment to the HIV LTR Promoter
Experiments in human cellsMetformin
Thursday, April 20
Preprints.org
Metformin Treatment Leads to Increased HIV Transcription and Gene Expression Though Increased CREB Phosphorylation and Recruitment to the HIV LTR Promoter
Preprint: experiments in human cellsMetformin
Tuesday, April 11
Journal of Clinical and Translational Research
Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderly subjects
Non-randomized trial in 35 peopleInterventions
Sunday, August 7
Cell Death & Disease
The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila
Experiments in fliesMechanisms
Wednesday, June 1
Biochemical and Biophysical Research Communications
Myricetin improves cognitive function in SAMP8 mice and upregulates brain-derived neurotrophic factor and nerve growth factor
Experiments in miceInterventions
Monday, September 13
Neurochemistry International
Vitamin B₁₂-folic acid supplementation regulates neuronal immediate early gene expression and improves hippocampal dendritic arborization and memory in old male mice
Experiments in miceInterventions
Sunday, November 1
Friday, March 1
Cellular Physiology and Biochemistry
Pterostilbene Improves Cognitive Performance in Aged Rats: An in Vivo Study
Experiments in ratsInterventions
Saturday, December 15
Aging Cell
Aging differentially modulates the Wnt pro-survival signalling pathways in vascular smooth muscle cells
Experiments in cellsMechanisms
Thursday, August 2
International Journal of Molecular Medicine
Piperlongumine decreases cognitive impairment and improves hippocampal function in aged mice
Experiments in miceCognitive impairment
Friday, June 15
Monday, November 28
Brain Research Bulletin
Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis
Experiments in ratsInterventions
Thursday, May 24
Journal of Neurochemistry
Spermidine-induced improvement of memory involves a cross-talk between protein kinases C and A
Experiments in ratsMechanisms
Saturday, June 25
Neurobiology of Learning and Memory
Hippocampal PKA/CREB pathway is involved in the improvement of memory induced by spermidine in rats
Experiments in ratsSpermidine
Friday, January 14
The Journal of Biological Chemistry
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
Experiments in miceSirtuin signaling