Corticotropin-stimulated adenylate cyclase activity

Advancing age is associated with corticotropin-stimulated adenylate cyclase activity in rats (4-fold stimulation at 1 month; 2-fold at 24 months).

“The fourfold stimulation by ACTH noted in the 1-mo-old animals decreased gradually with age but was still twice basal at 24 mo.”

Animalsadipocyte membrane

Hormone-sensitive fat cell adenylate cyclase in the rat. Influences of growth, cell size, and aging

The Journal of clinical investigation·1 Jan 1976