Coronary artery calcium presence

1. coronary artery calcium prediction model predicts coronary artery calcium presence in humans (asymptomatic Southeast Asian adults without known ASCVD; internal validation) (Apparent AUC 0.804 (95% CI 0.767–0.841); optimism-corrected AUC 0.799).

   “demonstrated moderate-to-good discrimination (apparent AUC 0.804, 95% CI: 0.767–0.841; optimism-corrected AUC 0.799).”

   Humansasymptomatic Southeast Asian adults without known ASCVD; internal validation351 (66.1%) malesn = 531

   Development and internal validation of a probability-based coronary artery calcium prediction model to refine cardiovascular risk

   ESC Congress 2026 abstract·Oct 26, 2026

1. Coronary artery calcium presence is associated with exaggerated blood pressure response during exercise in humans (Non-zero versus zero coronary artery calcium score) (OR 4.14, 95% CI 2.24–7.64).

   “carrying a 4.14-fold increase in the odds of EBPR (95% CI: 2.24–7.64, p < .001).”

   HumansNon-zero versus zero coronary artery calcium scoren = 351

   The "binary switch" of vascular aging: coronary artery calcium presence, but not density or volume, predicts exaggerated blood pressure response during exercise

   ESC Congress 2026 abstract·Oct 26, 2026

1. Life's Essential 8 is associated with coronary artery calcium presence in humans (OR 0.34, 95% CI 0.23-0.51).

   “for the presence of CAC were 0.34 (0.23-0.51) in the moderate and 0.25 (0.15-0.39) in the high CVH group.”

   HumansModerate baseline cardiovascular health score (50-<80) versus low (0-<50); fully adjusted analysiscoronary arteryMean follow-up of 7.3 years65.2% femalesn = 1,746

   Association between Cardiovascular Health by Life's Essential 8 and Subsequent Coronary Artery Calcium Score: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort

   Pulse (Basel, Switzerland)·Aug 6, 2026

More on Life's Essential 8