Coronary calcium volume

There are 3 papers on coronary calcium volume in aging research: 3 observational studies in people.

Biomarker

3 papers study it3 findings

2 new papers in 30 daysSee all 3

“high density/high volume: HR: 2.05 (95% CI:1.52-2.77)”
Effects of Concordance and Discordance of Coronary Calcium Density and Volume on Major Adverse Cardiac Event OutcomesAHA Scientific Sessions 2025 abstract2025doi:10.1161/circ.152.suppl_3.4366893
  • Humans3

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1

Exaggerated blood pressure response during exercise

no changein humans1

1 study
  1. Exaggerated blood pressure response during exercise was not clearly linked with coronary calcium volume in humans (Patients with versus without exaggerated blood pressure response) (291 ± 549 vs 254 ± 547 mm3).

    “nor were there significant differences in mean calcium volume (291 ± 549 vs 254 ± 547, p = 0.668)”

    HumansPatients with versus without exaggerated blood pressure response

    The "binary switch" of vascular aging: coronary artery calcium presence, but not density or volume, predicts exaggerated blood pressure response during exercise

    ESC Congress 2026 abstract

Associations

2

Epicardial adipose tissue thickness

upin humans1

1 study
  1. Epicardial adipose tissue thickness is associated with coronary calcium volume in humans (Stable coronary artery disease; never taken statins) (r=0.62, p=0.001).

    “in Group 2, EATT showed a positive correlation with CC volume (r= 0.62, p= 0.001)”

    HumansStable coronary artery disease; never taken statinscoronary arteryn = 35

    Relationship between epicardial adipose tissue thickness and coronary calcification in patients with stable coronary artery disease on chronic statin therapy

    ESC Congress 2026 abstract

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Major adverse cardiovascular events

upin humans1HR 2.05

1 study
  1. Coronary calcium volume is linked with a higher risk of major adverse cardiovascular events in humans (asymptomatic individuals with prevalent CAC, compared to low density/low volume) (HR 2.05 (95% CI: 1.52-2.77)).

    “high density/high volume: HR: 2.05 (95% CI:1.52-2.77)”

    Humansasymptomatic individuals with prevalent CAC, compared to low density/low volumemean follow-up 5.5 (±2.2) yearsn = 2,647

    Effects of Concordance and Discordance of Coronary Calcium Density and Volume on Major Adverse Cardiac Event Outcomes

    AHA Scientific Sessions 2025 abstract

More on Major adverse cardiovascular events

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