Contractile markers

1 paper1 finding

Animals1

Upstream

1

ERCC1

downin mice1

1 study

ERCC1 decreases contractile markers in mice.
“characterized by a decrease in contractile markers and a decrease in synthetic markers at the RNA level.”
AnimalsErcc1 deficiencyaorta
Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response
Aging cell7 Mar 2024

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Experiments in animalsMechanisms

Aging Cell7 Mar

Ercc1 DNA repair deficiency results in vascular aging characterized by VSMC phenotype switching, ECM remodeling, and an increased stress response

Experiments in miceDNA repair