Composite biomarker index
Biomarker1 paper2 findings
- Human trial1
Interventions
1Caloric restriction
upin humans1
1 study
Caloric restriction
upin humans1
Caloric restriction improves composite biomarker index in humans (-2.2).
Human trialpooled randomized CR trialsn = 829
Impact of caloric restriction on biological aging: insights from a composite biomarker index in older adults · GeroScience · 12 Sep 2026
Upstream
1Weight loss
mediatesin humans1
1 study
Weight loss
mediatesin humans1
Weight loss mediates composite biomarker index in humans (48.5% (95% CI 22.6 to 82.2%)).
Human trialmediation analysisn = 829
Impact of caloric restriction on biological aging: insights from a composite biomarker index in older adults · GeroScience · 12 Sep 2026