Combined serum total light chains

Combined serum total light chains are associated with mortality in humans (HR 1.891 (95% CI 1.347–2.654)).

“the highest quartiles of TLCκ, TLCλ, and ΣTLC were associated with an increased risk of death”

HumansHighest quartileMedian follow-up of 30 months18.8% malesn = 906

Associations of serum total light chain kappa and lambda levels with all-cause mortality in Chinese centenarians

Immunity & ageing : I & A·19 Jun 2025