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cis-eQTL AGE-PRS

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Executive function performance

upin humans1

1 study

  1. cis-eQTL AGE-PRS is associated with executive function performance in humans.

    “These structural findings co-occurred alongside increased executive function performance on the Trail Making Test B (pFDR=0.035)”

    Humansassessed using Trail Making Test Bn = 31,384

    Neurostructural and cognitive signatures of novel polygenic risk scores for molecular brain aging

    bioRxiv (Cold Spring Harbor Laboratory)20 Nov 2024Preprint

Frontal, temporal, and parietal cortical thickness

upin humans1

1 study

  1. cis-eQTL AGE-PRS is associated with frontal, temporal, and parietal cortical thickness in humans.

    “cis-eQTL AGE-PRS displayed robust associations with greater cortical thickness in age-sensitive frontal, temporal, and parietal regions”

    Humansfrontal, temporal, and parietal cortexn = 31,384

    Neurostructural and cognitive signatures of novel polygenic risk scores for molecular brain aging

    bioRxiv (Cold Spring Harbor Laboratory)20 Nov 2024Preprint

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