Circulating cell-free nuclear DNA integrity

1 paper1 finding

Humans1

Upstream

1

Extreme aging

downin humans1−21%

1 study

Extreme aging decreases circulating cell-free nuclear DNA integrity in humans (-20.7%).
“ccfnDNA integrity significantly decreased from CG to CEN (20.7%)”
Humans
Multiparametric profiling of plasma cell-free nucleic acids in nonagenarians and centenarians highlights age-related differences associated with longevity
GeroScience29 Nov 2025

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GeroScience29 Nov

Multiparametric profiling of plasma cell-free nucleic acids in nonagenarians and centenarians highlights age-related differences associated with longevity

Cross-sectional study of 86 peopleBiomarkers