CHST6

1. Alzheimer's disease is associated with CHST6 in humans.

   “during AD, bone related proteins Collagen A1(VI) and CHST6 are upregulated in males, whereas FGF‐19, IGFBP‐1, Chondrocalcin, FGF‐19, and IGFBP‐1 are downregulated compared to HC.”

   Humansmales with AD compared to HCplasmamales

   Age‐related bone associated comorbidity indicated as changes in the plasma bone and senescence markers in Alzheimer's disease patients

   AAIC 2025 abstract·25 Dec 2025

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