Cerebrovascular responsiveness to cognitive stimuli

There are 2 papers on cerebrovascular responsiveness to cognitive stimuli in aging research: 2 trials in people. The newest story, Oct 30, 2026: “Small trial suggests capsaicin may improve cognition”.

Biomarker

2 papers study it3 findings

1 new paper in 30 daysSee all 2

“A very strong relationship was observed between the number of exercise sessions completed and CVR to cognitive stimuli (r = 0.878, P < 0.001)”
The Effects of Aerobic Exercise Training on Cerebrovascular and Cognitive Function in Sedentary, Obese, Older AdultsFrontiers in aging neuroscience2022doi:10.3389/fnagi.2022.892343
  • Human trial2

Interventions

1

Aerobic exercise

upin humans1

1 study
  1. Aerobic exercise increases cerebrovascular responsiveness to cognitive stimuli in humans (25.9 ± 6.1% vs. 16.4 ± 5.4%, P < 0.001).

    “CVR to cognitive stimuli (25.9 ± 6.1% vs. 16.4 ± 5.4%, P < 0.001)”

    Human trial16 weeks

    The Effects of Aerobic Exercise Training on Cerebrovascular and Cognitive Function in Sedentary, Obese, Older Adults

    Frontiers in aging neuroscience

More on Aerobic exercise

Associations

2

Cognitive function

upin humans1

1 study
  1. Cerebrovascular responsiveness to cognitive stimuli is associated with cognitive function in humans (r = 0.685, P < 0.001).

    “There were positive correlations between the total composite cognitive score and CVR to hypercapnia (r = 0.474, P = 0.014) and CVR to cognitive stimuli (r = 0.685, P < 0.001).”

    Humans

    The benefits of regular aerobic exercise training on cerebrovascular function and cognition in older adults

    European journal of applied physiology

Aerobic exercise

upin humans1

1 study
  1. Aerobic exercise is associated with cerebrovascular responsiveness to cognitive stimuli in humans (number of exercise sessions completed) (r = 0.878, P < 0.001).

    “A very strong relationship was observed between the number of exercise sessions completed and CVR to cognitive stimuli (r = 0.878, P < 0.001)”

    Human trialnumber of exercise sessions completed

    The Effects of Aerobic Exercise Training on Cerebrovascular and Cognitive Function in Sedentary, Obese, Older Adults

    Frontiers in aging neuroscience

More on Aerobic exercise

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Nutrients

Small trial suggests capsaicin may improve cognition

Brain blood-flow responses during mental tasks rose from 18% to 21% with supplementation, versus a decline from 21% to 19% with placebo over 12 weeks.Brain blood-flow responses during mental tasks rose from 18% to 21% with supplementation, versus a decline from 21% to 19% with placebo over 12 weeks.

Randomized trial · 34 peopleInterventions