Cell-free DNA fragment patterns

1. Cell-free DNA fragment patterns predict chromatin and 3D genome organisation.

   “Cell-free DNA (cfDNA) fragment patterns provide a systemic, though lossy, readout of chromatin organization and thus of biological meaning collapse across tissues.”

   Review

   Chromatin Geometry Collapse as the Primary Driver of Aging and Disease

   Zenodo (CERN European Organization for Nuclear Research)·Mar 6, 2026Preprint

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