CD61(high)/CD49f(high) cells

1. Metformin decreases CD61(high)/CD49f(high) cells in mice.

   “systemic administration of metformin selectively inhibits CD61(high)/CD49f(high) subpopulation, a group of tumor-initiating cells (TIC) of mouse mammary tumor virus (MMTV)-ErbB2 mammary tumors, in preneoplastic mammary glands”

   Animalsin preneoplastic mammary glandssystemic administrationmammary gland

   Metformin selectively targets tumor-initiating cells in ErbB2-overexpressing breast cancer models

   Cancer prevention research (Philadelphia, Pa.)·9 Dec 2013

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