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CD3+CD8+ lymphocytes

Biomarker

1 paper studies it1 finding

  • Humans1

Associations

1

Immune effector cell-associated neurotoxicity syndrome

downin humans1OR 0.937

1 study

  1. CD3+CD8+ lymphocytes are associated with immune effector cell-associated neurotoxicity syndrome in humans (38.6% vs 46.8%, OR=0.937 [95% CI: 0.882-0.996]).

    “lower percentage of CD3+CD8+ lymphocytes (38.6% vs 46.8%, OR=0.937 [95% CI: 0.882-0.996], p=0.035) and higher levels of serum C-reactive protein (CRP, 4.52 mg/dl vs 1.00 mg/dl, OR=7.133 [95% CI: 1.796-28], p=0.005) are associated with ICANS”

    Humansat pre-lymphodepletionperipheral bloodn = 53

    Peripheral blood cellular profile at pre-lymphodepletion is associated with CD19-targeted CAR-T cell-associated neurotoxicity

    Frontiers in immunology

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