CD27-CD28- CD4+ T cells
1 paper3 findings
- Humans1
Interventions
2Epstein-barr virus infection
no changein humans1
1 study
Epstein-barr virus infection
no changein humans1
Epstein-barr virus infection has no effect on CD27-CD28- CD4+ T cells in humans.
“EBV and HSV did not independently increase CD27−CD28− CD4+ T cell frequency.”
Humans
Divergent Effects of Cytomegalovirus and Rheumatoid Arthritis on Senescent CD4⁺ T Cells
European journal of immunology1 Nov 2025
Cytomegalovirus infection
upin humans1
1 study
Cytomegalovirus infection
upin humans1
Cytomegalovirus infection increases CD27-CD28- CD4+ T cells in humans.
“In CMV-seropositive individuals, CD27−CD28− CD4+ T cells were abundant and exhibited a predominantly cytotoxic, nonproliferative phenotype.”
Humansin CMV-seropositive individuals
Divergent Effects of Cytomegalovirus and Rheumatoid Arthritis on Senescent CD4⁺ T Cells
European journal of immunology1 Nov 2025
Upstream
1Rheumatoid arthritis
no changein humans1
1 study
Rheumatoid arthritis
no changein humans1
Rheumatoid arthritis has no effect on CD27-CD28- CD4+ T cells in humans.
“Similarly, RA had little effect on their abundance”
Humans
Divergent Effects of Cytomegalovirus and Rheumatoid Arthritis on Senescent CD4⁺ T Cells
European journal of immunology1 Nov 2025