Alzheimer's & Dementia
Enzyme inhibitor reduced brain inflammation in mice
Daily injections for six weeks restricted immune-cell entry into the brain and restored cognitive function in male mice modeling Alzheimer's disease.Daily injections for six weeks restricted immune-cell entry into the brain and restored cognitive function in male mice modeling Alzheimer's disease.
Mouse studyInflammation
Who was studiedMale wild-type and Alzheimer's model mice, 6 weeks
What changedBrain inflammation was lower in inhibitor-treated Alzheimer's model mice than in saline-treated mice
The catchThe inhibitor could also affect B cells, monocytes, and dendritic cells