Cardiovascular autonomic age gap

Cardiovascular risk increases cardiovascular autonomic age gap in humans (+11 yr).

“At a 0.5% threshold, the high-CVR group showed a markedly increased CAA gap (+11 yr)”

Humanshigh-CVR group (0.5% threshold)

Quantifying cardiovascular autonomic aging with machine learning

American journal of physiology. Heart and circulatory physiology·25 Oct 2025

Cardiovascular autonomic age gap is associated with cardiovascular risk in humans (r = 0.31, P = 0.002).

“the CAA gap correlated with deviation from normative risk (r = 0.31, P = 0.002).”

Humans

Quantifying cardiovascular autonomic aging with machine learning

American journal of physiology. Heart and circulatory physiology·25 Oct 2025