PLOS Medicine
Blood protein scores may refine cardiovascular risk estimates
Protein scores reclassified 18.6% of people traditionally assessed as intermediate risk into high risk; their 10-year cardiovascular event rate was 10.9%.Protein scores reclassified 18.6% of people traditionally assessed as intermediate risk into high risk; their 10-year cardiovascular event rate was 10.9%.
Cohort · 1,835 peopleAtherosclerotic cardiovascular disease
Who was studied1,835 participants initially free of atherosclerotic cardiovascular disease
What changedAdding protein scores improved cardiovascular risk classification over traditional assessment alone (net reclassification improvement 0.127)
The catchProtein scores incorrectly moved 20 of 106 future cases from intermediate to low risk