Brain COMT

Biomarker

1 paper1 finding

  • Humans1

Associations

1

COMT

upin humans1

1 study
  1. COMT is associated with brain COMT in humans.

    “each additional Val allele was associated with higher brain COMT (p < 0.0001).”

    HumansCOMT Val158Metbraineach additional Val allele

    Diet’s link to dementia differed by gene variant in older adults

    Nutrients30 Sep 2026

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Nutrients

Diet’s link to dementia differed by gene variant in older adults

In one genetic group, each extra diet-score point was linked to lower relative Alzheimer’s dementia risk over time (hazard ratio 0.82).In one genetic group, each extra diet-score point was linked to lower relative Alzheimer’s dementia risk over time (hazard ratio 0.82).

Cohort study of 745 older adultsAll-cause dementia

Limit: Questionnaire-based diet estimates may misclassify adherence and distort genotype-specific associations