Braak V/VI staging

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Male sex

downin humans1

1 study
  1. Male sex is associated with Braak V/VI staging in humans (β = -0.40, p = 0.005).

    “male sex were associated with a lower prevalence of Braak‐V/VI neuropathology (β=‐0.25, p <0.001 and β=‐0.40, p = 0.005)”

    Humansmales

    Lower Antemortem [ ¹⁸ F]flortaucipir PET retention in Males and Older Individuals is Explained by Lower Postmortem Tau Tangle Density

    AAIC 2025 abstract8 Jan 2026

Age

downin humans1

1 study
  1. Age is associated with Braak V/VI staging in humans (β = -0.25, p < 0.001).

    “older age and male sex were associated with a lower prevalence of Braak‐V/VI neuropathology (β=‐0.25, p <0.001 and β=‐0.40, p = 0.005)”

    Humans

    Lower Antemortem [ ¹⁸ F]flortaucipir PET retention in Males and Older Individuals is Explained by Lower Postmortem Tau Tangle Density

    AAIC 2025 abstract8 Jan 2026

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