Braak neurofibrillary tangles stage >4

There is 1 paper on Braak neurofibrillary tangles stage >4 in aging research: 1 observational study in people.

Biomarker

1 paper studies it1 finding

See all 1 papers on Braak neurofibrillary tangles stage >4

“Individuals in the tenth decile of the score exhibited a twofold increased risk of presenting with Braak neurofibrillary tangles stage of >4”
Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementiasNature genetics2026doi:10.1038/s41588-026-02583-1
  • Humans1

Associations

1

Polygenic score combining the effects of ADRD loci other than APOE

upin humans1

1 study
  1. Polygenic score combining the effects of ADRD loci other than APOE is linked with a higher risk of Braak neurofibrillary tangles stage >4 in humans (excluding APOE loci, comparing tenth decile to median score group) (twofold increased risk).

    “Individuals in the tenth decile of the score exhibited a twofold increased risk of presenting with Braak neurofibrillary tangles stage of >4”

    Humansexcluding APOE loci, comparing tenth decile to median score group

    Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementias

    Nature genetics

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