Biological cardiovascular age

Biological cardiovascular age predicts major adverse cardiovascular events in humans (C-index 0.768 (95% CI 0.681–0.855), compared with 0.590 for chronological age).

“The accuracy for prediction of MACE was higher for bioAGE (c = 0.768; 95% CI: 0.681-0.855, p < 0.001)”

HumansSymptomatic patients with suspected coronary artery disease undergoing clinically indicated coronary CTABoth; 137 (39.6%) womensn = 346

Biological Cardiovascular Age Derived from Coronary CTA Reports Using a Large Language Model: A Novel Predictor of Major Adverse Cardiovascular Events?

Diagnostics (Basel, Switzerland)·26 Apr 2026