Papers on binding potential

28 papers

Wednesday, January 7

AAIC 2025 AbstractJan 7

PET/MR imaging of LC‐NE function for interrogation of health disparity in preclinical AD

Cohort study in peopleMechanisms

Paper

Tuesday, December 23

AAIC 2025 AbstractDec 23

PET/MR imaging of LC‐NE function for interrogation of health disparity in preclinical AD

Cohort study in peopleMechanisms

Paper

Sunday, November 30

Current Problems in CardiologyNov 30

Mechanisms and targets of vascular natural aging from a systems biology perspective

Computational studyMechanisms

Paper

Thursday, September 18

Ecotoxicology and Environmental SafetySep 18

Integrating network pharmacology and experimental validation to decipher the protective effect of icariin against testicular aging

Experiments in miceInterventions

Paper

Friday, April 12

Journal of Nuclear MedicineApr 12

PET Quantification of [¹⁸F]VAT in Human Brain and Its Test-Retest Reproducibility and Age Dependence

Cross-sectional study of 52 peopleBiomarkers

Paper

Wednesday, July 5

Frontiers in PharmacologyJul 5

Paeoniflorin mitigates high glucose-induced lifespan reduction by inhibiting insulin signaling in Caenorhabditis elegans

Experiments in wormsInterventions

Paper

Monday, January 16

The Journal of Prevention of Alzheimer's DiseaseJan 16

Associations of Stages of Objective Memory Impairment with Cerebrospinal Fluid and Neuroimaging Biomarkers of Alzheimer's Disease

Cohort study of 586 peopleAlzheimer's disease

Paper

Friday, February 11

Frontiers in Aging NeuroscienceFeb 11

The Aged Striatum: Evidence of Molecular and Structural Changes Using a Longitudinal Multimodal Approach in Mice

Experiments in miceMechanisms

Paper

Saturday, December 18

Journal of Nuclear MedicineDec 18

Comparison of ¹¹C-Pittsburgh Compound B and ¹⁸F-Flutemetamol White Matter Binding in PET

Cohort study of 61 peopleBiomarkers

Paper

Friday, May 28

Research SquareMay 28

Targeted Downregulation of Estradiol Binding Na+/H+ Exchanger Nhx-2, Mimics Calorie Restriction, Extends Reproductive Longevity and Ameliorates Effects Associated With Alpha Synuclein Aggregation In C. Elegans

Preprint: experiments in wormsMechanisms

Paper

Friday, November 13

Brain Structure & FunctionNov 13

Cortical thickness mediates the relationship between DRD2 C957T polymorphism and executive function across the adult lifespan

Study in peopleMechanisms

Paper

Thursday, July 30

bioRxivJul 30

Targeted downregulation of estradiol binding Na + /H + exchanger nhx-2, mimics calorie restriction, extends reproductive longevity and ameliorates effects associated with alpha synuclein aggregation in C. elegans

Preprint: experiments in wormsMechanisms

Paper

Wednesday, October 9

NeuroImageOct 9

Age-differential relationships among dopamine D1 binding potential, fusiform BOLD signal, and face-recognition performance

Study in peopleMechanisms

Paper

Monday, July 29

NeuroImageJul 29

Higher striatal D2-receptor availability in aerobically fit older adults but non-selective intervention effects after aerobic versus resistance training

Trial in peopleInterventions

Paper

Sunday, May 19

Molecular Imaging and BiologyMay 19

GABAA Receptors in the Mongolian Gerbil: a PET Study Using [¹⁸F]Flumazenil to Determine Receptor Binding in Young and Old Animals

Experiments in animalsMechanisms

Paper

Tuesday, April 2

Human Brain MappingApr 2

Differential regional decline in dopamine receptor availability across adulthood: Linear and nonlinear effects of age

Study in peopleMechanisms

Paper

Friday, June 15

Cerebral CortexJun 15

Neurocognitive Profiles of Older Adults with Working-Memory Dysfunction

Study in peopleMechanisms

Paper

Sunday, April 8

Journal of Nuclear MedicineApr 8

Age-Related Change in 5-HT₆ Receptor Availability in Healthy Male Volunteers Measured with ¹¹C-GSK215083 PET

Study in peopleMechanisms

Paper

Saturday, January 13

Frontiers in PharmacologyJan 13

Age-Related Decrease in Male Extra-Striatal Adenosine A₁ Receptors Measured Using¹¹C-MPDX PET

Study in peopleMechanisms

Paper

Thursday, November 2

Journal of Cerebral Blood Flow and MetabolismNov 2

Partial-volume correction increases estimated dopamine D2-like receptor binding potential and reduces adult age differences

Cross-sectional study in peopleBiomarkers

Paper

Tuesday, September 26

ObesitySep 26

Caloric Restriction-Induced Decreases in Dopamine Receptor Availability are Associated with Leptin Concentration

Non-randomized trial in 15 peopleInterventions

Paper

Saturday, March 4

NeuroImageMar 4

Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D2/3 receptors and sub-cortical volumes in the human basal ganglia: A PET study with ¹⁸F-MNI-659 and ¹¹C-raclopride with correction for partial volume effect

Cohort study of 40 peopleMechanisms

Paper

Friday, December 23

NeuroImage ClinicalDec 23

Use of T1-weighted/T2-weighted magnetic resonance ratio to elucidate changes due to amyloid β accumulation in cognitively normal subjects

Cohort study in peopleBiomarkers

Paper

Thursday, April 28

Journal of Cerebral Blood Flow and MetabolismApr 28

Depiction of microglial activation in aging and dementia: Positron emission tomography with [¹¹C]DPA713 versus [¹¹C]( R)PK11195

Cross-sectional study in peopleDementia

Paper

Tuesday, February 16

NeuroImageFeb 16

Age-related changes in binding of the D2/3 receptor radioligand [(11)C](+)PHNO in healthy volunteers

Cross-sectional study of 42 peopleMechanisms

Paper

Tuesday, November 11

NeuroImageNov 11

Effects of estrogen and testosterone treatment on serotonin transporter binding in the brain of surgically postmenopausal women--a PET study

Non-randomized trial in 10 peopleTestosterone

Paper

Friday, January 1

Annals of NeurologyJan 1

APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

Cohort study of 241 peopleAlzheimer's disease

Paper

Saturday, May 1

Mechanisms of Ageing and DevelopmentMay 1

Phencyclidine-binding sites in mouse cerebral cortex during development and ageing: effects of inhibitory amino acids

Experiments in animalsMechanisms

Paper