MechanismsHumans
PET/MR imaging of LC‐NE function for interrogation of health disparity in preclinical AD
AAIC 2025 Abstract
Abstract
Background: Locus Coeruleus (LC) is the earliest location for tauopathy and its decline is highly correlated with AD symptomatology. The LC‐NE system produces functional adaptive changes in response to chronic stress. [ ¹¹ C]MRB‐PET allows in vivo quantification of NE transporter (NET) in humans.
The paper
Anmol S Bhatia, Andrew Kelleher, Ujjval Chopra, Ding's Lab
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Jennifer Bernal, Sachita Gupta, Matthew Arthur, Oliver Cesar, Artem Mikheev, jingyun chen, Henry Rusinek, Yu‐Shin Ding,New York University
AAIC 2025 Abstract · 7 Jan 2026 · CC BY
Presented at AAIC 2025


