Beta amyloid plaque load

1. Oldest-old age is associated with beta amyloid plaque load in humans.

   “For the oldest-old group, lower cortical volume, increased β-amyloid plaque load, prevalence of SVCD, and lower cognitive performance in the normal range were found.”

   Humanscognitively unimpaired; compared with younger-old participantsbrainn = 44

   Low cortical iron and high entorhinal cortex volume promote cognitive functioning in the oldest-old

   Neurobiology of aging·Dec 20, 2017

1. Entorhinal cortex volume is associated with beta amyloid plaque load in humans.

   “Moreover, only in the oldest-old, entorhinal cortex volume positively correlated with β-amyloid plaque load.”

   Humanscognitively unimpaired oldest-old participantsentorhinal cortexn = 44

   Low cortical iron and high entorhinal cortex volume promote cognitive functioning in the oldest-old

   Neurobiology of aging·Dec 20, 2017

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