Augmentation index
Biomarker6 papers5 findings
- Human trial1
- Humans3
Interventions
1Electronic cigarettes
upin humans1Moderate certainty
1 study
Electronic cigarettes
upin humans1Moderate certainty
Electronic cigarettes increase augmentation index in humans (SMD=1.05 [95% CI: 0.34-1.76, p=0.008]).
Reviewnicotine-containing products exposuren = 190
Acute Effects of Electronic Cigarettes and Heated Tobacco Products on Vascular Stiffness: A Systematic Review and Meta-Analysis · Current cardiology reviews · 25 Aug 2026
Upstream
1Obesity
upin humans1
1 study
Obesity
upin humans1
Obesity increases augmentation index in humans.
Humansin young adults aged 18-25 yearsn = 132
Impact of obesity on arterial health among young adults: A bioelectrical impedance study · Bioinformation · 31 May 2026
Associations
310-year ASCVD risk
upin humans1
1 study
10-year ASCVD risk
upin humans1
Augmentation index is associated with 10-year ASCVD risk in humans (r = 0.236).
Humansleft ventricular ejection fraction >55%n = 3,354
Functional Markers of Vascular Aging: Subendocardial Viability Ratio, Augmentation Pressure, and Augmentation Index as Links to Atherosclerotic Cardiovascular Disease Risk · Journal of clinical hypertension (Greenwich, Conn.) · 1 Sep 2026
Fasting blood glucose
downin humans1OR 0.91
1 study
Fasting blood glucose
downin humans1OR 0.91
Fasting blood glucose is associated with augmentation index in humans (OR 0.91, 95% CI 0.87-0.94).
Humansadjusted for several clinical characteristicsn = 6,617
Glycemia, Insulin Sensitivity Markers and Arterial Stiffness: The Framingham Heart Study · Hypertension (Dallas, Tex. : 1979) · 26 Aug 2026
HbA1c
downin humans1OR 0.86
1 study
HbA1c
downin humans1OR 0.86
HbA1c is associated with augmentation index in humans (OR 0.86, 95% CI 0.78-0.95).
Humansadjusted for several clinical characteristicsn = 6,617
Glycemia, Insulin Sensitivity Markers and Arterial Stiffness: The Framingham Heart Study · Hypertension (Dallas, Tex. : 1979) · 26 Aug 2026