Augmentation index

Biomarker6 papers5 findings

  • Human trial1
  • Humans3

Interventions

1

Electronic cigarettes

upin humans1Moderate certainty

1 study
  1. Electronic cigarettes increase augmentation index in humans (SMD=1.05 [95% CI: 0.34-1.76, p=0.008]).

    Reviewnicotine-containing products exposuren = 190

    Acute Effects of Electronic Cigarettes and Heated Tobacco Products on Vascular Stiffness: A Systematic Review and Meta-Analysis · Current cardiology reviews · 25 Aug 2026

Electronic cigarettes →

Upstream

1

Obesity

upin humans1

1 study
  1. Obesity increases augmentation index in humans.

    Humansin young adults aged 18-25 yearsn = 132

    Impact of obesity on arterial health among young adults: A bioelectrical impedance study · Bioinformation · 31 May 2026

Associations

3

10-year ASCVD risk

upin humans1

1 study
  1. Augmentation index is associated with 10-year ASCVD risk in humans (r = 0.236).

    Humansleft ventricular ejection fraction >55%n = 3,354

    Functional Markers of Vascular Aging: Subendocardial Viability Ratio, Augmentation Pressure, and Augmentation Index as Links to Atherosclerotic Cardiovascular Disease Risk · Journal of clinical hypertension (Greenwich, Conn.) · 1 Sep 2026

10-year ASCVD risk →

Fasting blood glucose

downin humans1OR 0.91

1 study
  1. Fasting blood glucose is associated with augmentation index in humans (OR 0.91, 95% CI 0.87-0.94).

    Humansadjusted for several clinical characteristicsn = 6,617

    Glycemia, Insulin Sensitivity Markers and Arterial Stiffness: The Framingham Heart Study · Hypertension (Dallas, Tex. : 1979) · 26 Aug 2026

Fasting blood glucose →

HbA1c

downin humans1OR 0.86

1 study
  1. HbA1c is associated with augmentation index in humans (OR 0.86, 95% CI 0.78-0.95).

    Humansadjusted for several clinical characteristicsn = 6,617

    Glycemia, Insulin Sensitivity Markers and Arterial Stiffness: The Framingham Heart Study · Hypertension (Dallas, Tex. : 1979) · 26 Aug 2026

HbA1c →

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