ATVTfR brain exposure

1 paper1 finding

Animals1

Upstream

1

Early development

upin mice1

1 study

Early development increases ATVTfR brain exposure in mice.
“neonates exhibited significantly elevated levels of vascular TfR protein and ATVTfR brain exposure compared to adult mice”
Animalsbrain
Transferrin receptor-mediated transport at the blood-brain barrier is elevated during early development and maintained across aging and in an Alzheimer's mouse model
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism16 Aug 2025

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Journal of Cerebral Blood Flow and Metabolism16 Aug

Transferrin receptor-mediated transport at the blood-brain barrier is elevated during early development and maintained across aging and in an Alzheimer's mouse model

Experiments in miceAlzheimer's disease