AT8

AT8 is associated with trafficking defects in flies.

“increased p ‐tau levels correlated with downstream vesicular and mitochondrial trafficking defects in some neurons but not all”

Model organismsexpression of hTau0N3Rbrain

Characterising differential vulnerability of neurons to tau‐mediated toxicity

AAIC 2025 abstract·23 Dec 2025

AT8 is associated with neurodegeneration in flies.

“degeneration correlated with significant age‐dependent increases in phospho‐tau levels in the same neuron type”

Model organismsexpression of hTau0N3Rbrain

Characterising differential vulnerability of neurons to tau‐mediated toxicity

AAIC 2025 abstract·23 Dec 2025