APOE ε4 allele frequency

Cognitively healthy centenarian status is associated with APOE ε4 allele frequency in humans (2.3-fold depletion; p = 6.3 × 10−7).

“the APOE-ε4 allele was 2.3-fold depleted (p = 6.3 × 10−7).”

HumansCognitively healthy centenarians compared with 60–80-year-old population controls

The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description

European journal of epidemiology·Oct 25, 2018