Anti-cardiolipin autoantibody

1. Caloric restriction decreases anti-cardiolipin autoantibody in mice.

   “Mean anti-cardiolipin autoantibody titers and mean levels of circulating immune complexes were also lowered in RCI mice when all RCI mice were compared to ad libitum fed group A mice.”

   Animalsin male (NZW x BXSB)F1 micemales

   Calorie restriction prevents the occlusive coronary vascular disease of autoimmune (NZW x BXSB)F1 mice

   Proceedings of the National Academy of Sciences of the United States of America·May 10, 1994

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1. Anti-cardiolipin autoantibody raises the risk of severe COVID-19 in humans.

   “anti-cardiolipin and anti-platelet glycoprotein autoantibodies significantly increased the likelihood of developing a severe COVID-19 phenotype with aging”

   Humanswith aging

   Severe COVID-19 patients exhibit elevated levels of autoantibodies targeting cardiolipin and platelet glycoprotein with age: a systems biology approach

   npj aging·Aug 24, 2023

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