Aneuploidy cells

1. EIF5A2 increases aneuploidy cells in mice.

   “a significantly increase in number of aneuploidy cells (p < 0.05) resulted from an increase in the incidences of misaligned and lagging chromosomal materials”

   Animalstransgenic mice

   Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability

   BMC cancer·May 26, 2011

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