Androgen clock
1 paper3 findings
- Animals1
Interventions
2Castration
downin O. aries1
1 study
Castration
downin O. aries1
Castration inhibits androgen clock in O. aries.
“removal of androgens by castration in sheep completely halted the androgen clock”
Animals
The androgen clock is an epigenetic predictor of long-term male hormone exposure
Proceedings of the National Academy of Sciences of the United States of America13 Jan 2025
Dihydrotestosterone
upin mice1
1 study
Dihydrotestosterone
upin mice1
Dihydrotestosterone increases androgen clock in mice.
“can be accelerated beyond that in normal male mice by supplementing females with dihydrotestosterone”
Animalsfemales
The androgen clock is an epigenetic predictor of long-term male hormone exposure
Proceedings of the National Academy of Sciences of the United States of America13 Jan 2025
Upstream
1AR
mediatesin animals1
1 study
AR
mediatesin animals1
AR mediates androgen clock.
“show its "tick" is mediated by the androgen receptor”
Animals
The androgen clock is an epigenetic predictor of long-term male hormone exposure
Proceedings of the National Academy of Sciences of the United States of America13 Jan 2025