α-syn::YFP fluorescence

1. Spiraeoside decreases α-syn::YFP fluorescence in worms (32%).

   “spiraeoside and miquelianin as key constituents, reducing the α-syn::YFP fluorescence by 32% and 35% at 200 μg/mL, respectively”

   Model organismsNL5901200 μg/mL

   Miquelianin and spiraeoside from Filipendula ulmaria mitigate α-synuclein accumulation in C.elegans and reduce the expression of neuroinflammatory cytokines in human microglia

   Frontiers in pharmacology·11 Feb 2026

More on Spiraeoside

1. Miquelianin decreases α-syn::YFP fluorescence in worms (35%).

   “miquelianin as key constituents, reducing the α-syn::YFP fluorescence by 32% and 35% at 200 μg/mL, respectively”

   Model organismsNL5901200 μg/mL

   Miquelianin and spiraeoside from Filipendula ulmaria mitigate α-synuclein accumulation in C.elegans and reduce the expression of neuroinflammatory cytokines in human microglia

   Frontiers in pharmacology·11 Feb 2026

More on Miquelianin

1. Filipendula ulmaria decreases α-syn::YFP fluorescence in worms (up to 25%).

   “FE extended lifespan, improved health span and reduced α-syn::YFP fluorescence in NL5901 by up to 25% at 200 μg/mL.”

   Model organismsNL5901200 μg/mL

   Miquelianin and spiraeoside from Filipendula ulmaria mitigate α-synuclein accumulation in C.elegans and reduce the expression of neuroinflammatory cytokines in human microglia

   Frontiers in pharmacology·11 Feb 2026

More on Filipendula ulmaria