AI-PPG age gap

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Mortality

upin humans1OR 1.02

1 study
  1. AI-PPG age gap is associated with mortality in humans (OR 1.02, p = 0.01).

    “each one-year increase in AI-PPG age gap is associated with higher in-hospital mortality (odds ratio of 1.02, p = 0.01).”

    Humanseach one-year increase in AI-PPG age gap

    Artificial intelligence-derived photoplethysmography age as a digital biomarker for cardiovascular health

    Communications medicine19 Nov 2025

Major adverse cardiovascular and cerebrovascular events

upin humans1HR 2.37

1 study
  1. AI-PPG age gap raises the risk of major adverse cardiovascular and cerebrovascular events in humans (HR 2.37, p = 8.46 × 10−80).

    “participants with an AI-PPG age gap greater than 9 years have a significantly higher risk of major adverse cardiovascular and cerebrovascular events (hazard ratio of 2.37, p = 8.46 × 10−80)”

    HumansAI-PPG age gap greater than 9 years, after adjusting for key confounders

    Artificial intelligence-derived photoplethysmography age as a digital biomarker for cardiovascular health

    Communications medicine19 Nov 2025

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